|Title:||A study of two ubiquitous inexpensive predictive markers for SARS-CoV-2 to guide testing in regions of depleted resources.|
|Author(s):||R. Keane C. McGarvey A. Basirat C. Varghese|
|Institution:||Tallaght University Hospital|
|Poster:||Click to view poster|
|Abstract:||The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has been progressing globally since December 2019. This unforeseen outbreak is placing a significant stress on diagnostic laboratories. The negative impact of the delay in diagnosis of infectious diseases has been extensively studied. |
The aim of this retrospective, single centre study was to determine the efficacy of lymphopaenia and bilateral infiltrates on chest radiography as predictors of SARS-CoV-2 to provide guidance for the prioritisation of testing.
149 patients with suspected SARS-CoV-2 admitted to a Level-4 hospital in Ireland from April 1st to April 14th 2020 were identified. 46 patients had both lymphopenia and bilateral infiltrates and 69.56% (n=32) of these patients were SARS-CoV-2 ‘detected’. These markers combined provided a sensitivity of 84.21% with specificity of 70.21% when using RT-PCR for SARS-CoV-2 as a reference.