Accuracy of Multidisciplinary Team Consensus for Lung Cancer Resection in the absence of pre-operative histology: A five-year experience.

Title: Accuracy of Multidisciplinary Team Consensus for Lung Cancer Resection in the absence of pre-operative histology: A five-year experience.
Author(s): J Whooley R Weedle A White D Breen A Soo
Institution: University Hospital Galway
Poster: Click to view poster
Category: Lung Cancer and Bronchoscopy
Abstract: Lung resection remains the cornerstone of treatment for non-small cell lung cancer (NSCLC). British Thoracic Society (BTS) guidelines recommends pursuing pre-operative diagnosis and staging as much as possible. In the absence of pre-operative histological diagnosis, surgical treatment can be offered in conjunction with multidisciplinary team (MDT) and patient consensus. We aimed to assess the accuracy of our thoracic MDT in recommending treatment for those with suspected NSCLC in patients who do not have a confirmed pre-operative histological diagnosis.

A retrospective review was performed of patients undergoing lung resection at the recommendation of the thoracic MDT for suspected NSCLC in our unit between May 2016 and August 2021. Patients with confirmed histological diagnosis were excluded from analysis.

234 patients underwent lung resection without pre-operative histology in the five-year period. 54.6% were female, mean age was 67.4 years. Overall, the positive predictive value of the MDT team consensus for lung malignancy in the absence of pre-operative histology was 88.9% (true positive n=208/234.)

Performing lung resection in the absence of pre-operative histology is reasonable if done in conjunction with MDT consensus and appropriate patient counselling, in keeping with the British Thoracic Society Guidelines.