|Title:||Characteristics and clinical outcomes of patients requiring non-invasive ventilation for management of COVID-19 pneumonia|
|Author(s):||F O'Hannigan D O'Flaherty C McGeoghegan B Cushen|
|Poster:||Click to view poster|
|Abstract:||Non-invasive ventilation(NIV) for the management of COVID-19 induced hypoxaemic acute respiratory failure was commonly employed during the pandemic. The characteristics of patients requiring NIV on a specialist respiratory unit and clinical outcomes were retrospectively examined.|
The medical notes of ninety-three patients were reviewed. The mean age was 68 (14) years. The majority (60%) were male and 84% were overweight or obese. Multimorbidity was common (75%). All patients had a ceiling of care established; 57% for full escalation of care including intubation and 43% for ward-level care. Median time to NIV initiation was 2 days. NIV continued for >72 hours in 70% of patients. Overall 58% of patients recovered to discharge. Of those who survived, the median length of hospital stay was 15.5 (2-60) days.
Over 75% of patients for full escalation survived, 54% required intubation. Intubated patients had more pronounced hypoxaemia at hospital admission and prevalence of co-morbidity was greater.
NIV can be used effectively to manage respiratory failure due to COVID-19 pneumonia in the appropriate patient and setting. Additionally patients can successfully tolerate a prolonged duration of therapy. Identification of those most at-risk and early intensivist involvement is important to ensure timely escalation of treatment if required.