|Title:||Characteristics of Chronic Rhinosinusitis in Severe Asthma Cohort.|
|Author(s):||M Talty H Mulryan M Harrison M Thornton A O'Regan|
|Institution:||Galway University Hospital|
|Poster:||Click to view poster|
|Category:||Asthma and COPD|
|Abstract:||Chronic rhinosinusitis is an important cause of poor asthma control yet there is little prospective data on risk factors and impact of CRS treatment. We established a prospective study utilising a combined asthma – ENT clinic to assess this patient group. We report the characteristics of the first 40 patients in this study. |
Patients recruited from the Asthma clinic in GUH were assessed and managed in a standardised manner using a multidisciplinary team.
40 asthmatics (mean age 57 +/- & 21 male) were studied with evidence of CRS (Luck Mckay Score 11+7). By RAST testing (22/39) 56% were atopic (HDM 1; Grass 12; Tree 3; Dog 5; Cat 6) Aspergillus sensitization was seen in 7(17%). 30/39 (76%) had eosinophilia including 12/17 of the non-atopic cases. Other results included ANCA (2); ANA (4); Low immunoglobulins (3) and alpha 1 antitrypsin deficiency (2); 2 aspirin exacerbated.
CRS in asthma, although often atopic. is associated with eosinophilia and aspergillus sensitization. Further studies relating to risk factors and management are ongoing in this prospective cohort.