Organising Pneumonia as a Complication of SARS-COV-2 Infection

Title: Organising Pneumonia as a Complication of SARS-COV-2 Infection
Author(s): N Rajendran A Houston E Moore A Carolan B Kent B Kennedy
Institution: St. James's Hospital, Dublin
Poster: Click to view poster
Category: COVID 19
Abstract: Organizing pneumonia (OP) can occur in a small number of patients following initial resolution of SARS-COV-2 infection. We aimed to analyse the outcome of OP in COVID-19 patients.
A retrospective single-centre cohort study was used to assess a total of 6 patients who developed OP following resolution of COVID pneumonia admitted to the COVID unit in St James’ Hospital between 01/12/2020 and 01/05/2021. Patients were categorised based on their oxygen requirement, CT imaging, steroid therapy, duration of hospital stay, and clinical outcome.
The mean age was 70.8 years, with mean CRP 110±49.8. 5 (83%) patients were male. The median (range) onset developing OP from positive RT-PCR was 17 (9-22) days. 4 (66%) required high flow nasal oxygen (HFNO) therapy; no patients needed invasive ventilation. The median (range) daily prednisolone dosing was 40 (40-60) mg, and hospital stay 46(6-52) days. Of these 6, one died within 3 days of treatment.
We achieved a favourable outcome in most patients with early introduction of steroid, thereby regressing lung injury. Therefore, it is important to recognize and treat the unpredictable patterns post-COVID infection.