|Title:||Physical activity and sedentary behaviour in adults with Cystic Fibrosis – association with aerobic capacity, lung function, sleep, well-being, and quality of life: An observational study|
|Author(s):||M Curran A Tierney L Collins L Kennedy C McDonnell AJ Jurascheck A Sheikhi B Button B Casserly R Cahalan|
|Institution:||University of Limerick|
|Poster:||Click to view poster|
|Category:||CF and Pulmonary Infections|
|Abstract:||Physical activity (PA) and sedentary behaviour (SB) have marked impact on key prognostic indicators such as aerobic capacity and lung function in people with Cystic Fibrosis (CF), and may have associations with sleep, well-being, and health-related quality of life (HRQOL). |
This observational study assessed PA, SB, aerobic capacity, spirometry, sleep, well-being and HRQOL in adults with CF at University Hospital Limerick. PA/SB were assessed using an ActivPAL accelerometer worn for seven days. A cardiopulmonary exercise test evaluated aerobic capacity. Spirometry was performed according to American Thoracic Society guidelines. Well-being was measured by the AWESCORE, sleep quality by the Pittsburgh Sleep Quality Index (PSQI) and HRQOL using the CF Questionnaire-Revised (CFQR).
Thirty-three participants (13M/20F) were recruited. Mean (Standard Deviation (SD) age was 26.2 years (± 7.1 SD), with mean (SD) forced expiratory volume in 1-second (FEV1) 72.9% (±26.2 SD). Mean step count was 7788 (± 3583 SD). Over 75% of participants did not reach recommended PA targets (>10,000 steps), with females being 25.5% less active than males. The PSQI indicated 48.5% of participants scored >5, indicating poor sleep quality. Number of steps and SB demonstrated a moderate significant correlation with FEV1 (r=0.45, p=.030; r=-0.37, p=.043 respectively) and sleep quality (r=-0.85, p<.0001; r=0.77, p<.0001 respectively). VO2 peak expressed relative to body weight, and as a percentage of predicted, was significantly positively correlated with step count (r=0.48, p=.007; r=0.42, p=.022 respectively), but did not correlate with SB (p=.96). VO2 peak (l/m) strongly correlated with FEV1 (r=0.75, p<.0001).
Lower step count was significantly correlated to lower FEV1, lower aerobic capacity and poorer self-reported sleep quality.