| Title: | Preliminary results from a multi-centre trial evaluating the clinical and cost-effectiveness of lung volume reduction surgery. |
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| Author(s): | K Mulryan K Redmond |
| Institution: | Beacon Hospital, Sandyford. |
| Poster: | Click to view poster |
| Category: | COPD/Asthma |
| Abstract: | INTRODUCTION: Lung Volume Reduction (LVR) is a surgical technique to palliative dyspnoea by reducing residual volume (RV) for patients with advanced emphysema that have failed optimal medical therapy. It can be carried out via bronchoscopic lobar reduction with endobronchial valves (EBV) or keyhole surgery (VATS or robotic assisted thoracic surgery; RATS) with resection of hypoperfused tissue. METHOD As part of a clinical trial evaluating the costeffectiveness and clinical outcomes of LVR for a multi-centre cohort of patients with end-stage emphysema; we present the initial results of 20 patients. Workup includes smoking cessation, pulmonary rehabilitation, PFTs, VQ scan, high resolution CT-thorax non-contrast to generate a STRATX report evaluating interlobar fissures, 6-minute-walk test, preoperative assessment and quality of life(QOL) questionnaires (EQ-5D-5L and SGRQ). Results The mean age of this patient cohort is 66.7 (49–80), their mean FEV1 28.05 (16–43) and mean residual volume 206.8(147–290). 4 patients underwent VATS LVRS, 1 RATS and 15 had EBV. Preliminary results from patients who have completed 3 months follow-up show a mean increase in FEV1 to 33.8 (28 – 47) and mean decrease in RV to 173.4(145 – 201). Total SGRQ scores decreased from 67.1 to 51.22. Conclusion LVR is an effective treatment for dyspnoea with improvement in clinical and patient reported parameters. |
